Video footage from the KXAS-TV/NBC station in Fort Worth, Texas, to accompany a news story.

Effect of mescaline analogues on the behavior of cats. A laboratory technician puts a cat in an observation case. A test conducted at Aero Medical Laboratory in the United States shows reactions of the cat while under the influence of 3,4,5-Trimethylphenethylamine Thorazine. The psychoactive drug brings about temporary changes in the normal activities of the cat. The cat is in the observation case. It feels drowsy, is not able to stand and becomes inactive. Another cat kept in the observation case under the same medication also feels drowsy, is lying on its back and is unable to get up. Location: United States USA. Date: 1957.

Thorazine Shuffle

O.C. 750 SOF/MAG/SIL VS FORMER MENTAL HEALTH INSTITUTE INMATES AND PSYCHIATRIC PATIENTS MARCHING THROUGH STREETS OF PHILADELPHIA, CARRYING SIGNS AGAINST "FORCED DRUGGING OF INMATES". CHANTING ANTI-DRUG SLOGANS. CU'S WOMEN SINGING SONGS RELATED TO INMATES' CAUSE. VS MARCHERS ARRIVING FRONT OF "SMITH, KLINE AND FRENCH LABORATORIES". VS WOMEN READING STATEMENTS OPPOSING USE OF DRUGS TO "CURE" MENTAL PATIENTS. VS MEN AND OTHER WOMEN READING SIMILAR STATEMENTS. VS INTVS/W FORMER MENTAL HOSPITAL INMATES ON PREVIOUS EXPERIENCES WITH "THORAZINE", DANGERS OF THORAZINE, IMPROVED CONDITIONS FOLLOWING TERMINATION OF SAID DRUG USE. ETC. CI: HEALTH: MENTAL HEALTH. DEMONSTRATION, DOMESTIC: PA. DRUGS: THORAZINE. CIVIL RIGHTS: MISCELLANEOUS.

OC 1000 SOF MAG ROLL A FTG OF PRISON WARDEN CRACK DOWN. INTV W/ WARDEN FENTON OF LEWISBURG FEDERAL PRISON. TELLS OF REORGANIZING PRISON TO SEPARATE VIOLENT INMATES FROM OTHERS, IMPROVE REHABILITATION PROGRAMS. TELLS OF INSTITUTING SECURITY CRACK DOWN. VS GUARDS GOING THROUGH CELLS, INMATES PERSONAL BELONGINGS. VS WARDEN TOURING CELL BLOCKS. INTV W/ INMATES WHO TELLS OF REPRESSIVE PROGRAMS INSTITUTED BY WARDEN FENTON, LONG PERIODS OF SOLITARY CONFINEMENT, DRUGGING W/ THORAZINE TECHNIQUES, HOW IT INCREASES TENSION IN PRISON. INTV W/ VARIOUS INMATES ON FENTON PROGRAMS.

TONIGHT'S EXECUTION OF A BRITISH NATIVE ON GEORGIA'S DEATH ROW WILL TAKE PLACE AS SCHEDULED. THAT AFTER THE STATE'S PAROLE BOARD TURNED DOWN A LAST-MINUTE PLEA FOR MERCY FOR NICHOLAS INGRAM, SET TO DIE IN THE ELECTRIC CHAIR TONIGHT FOR THE 1983 MURDER OF A GEORGIA MAN. THE MAN'S WIFE SURVIVED THE ATTACK AND IDENTIFIED INGRAM AS HER HUSBAND'S KILLER.  YESTERDAY, A STATE JUDGE REJECTED CLAIMS THAT INGRAM WAS UNDER THE INFLUENCE OF THE DRUG "THORAZINE" AT HIS TRIAL. INGRAM'S ATTORNEYS SAY THE DRUG MAKES HIM APPEAR EMOTIONLESS AND SHOW NO REMORSE. THE CASE IS FRONT PAGE NEWS IN ENGLAND, WHERE INGRAM HOLDS DUAL CITIZENSHIP. THERE IS NO DEATH PENALTY IN ENGLAND.

Thorazine Shuffle

COVER FTG AND INTV FOR DEBORAH AMOS CS ON BREAKTHROUGHS IN TREATING THE DISEASE OF SCHIZOPHRENIA: AUDIOTAPES OF WHAT SCHIZOPHRENICS HEAR, NEW TECHNIQUES IN BRAIN IMAGING, AND NEW MEDICATIONS. 03:00:40 MS FOUR IMAGES OF BRAIN W/ UPPER LEFT IMAGE HIGHLIGHTING REGION JUST BEHIND THE FOREHEAD KNOWN AS THE PREFRONTAL CORTEX WHERE AUDITORY HALLUCINATION IS VISIBLE ALONG W/ TWO OTHER KIND OF PSYCHOTIC SYMPTOMS, DELUSIONS OR PARANOIA AND THOUGHT DISORGANIZATION AS EXPLAINED SOT BY DR ALAN BREIER. 03:01:31 CU UPPER LEFT IMAGE. 03:02:39 SOT ON DOPAMINE WHICH IS A NEUROCHEMICAL IN HUMAN BRAIN THOUGHT TO BE INVOLVED W/ SCHIZOPHRENIA. 03:03:17 CU IMAGE OF BRAIN OF NORMAL INDIVIDUAL W/ DOCTOR'S FINGER POINTING TO HIGHLIGHTED REGION. THIS INDIVIDUAL WAS GIVEN A DRUG CALLED KETAMINE (SP?) WHICH CAN REPRODUCE SOME OF THE SYMPTOMS OF SCHIZOPHRENIA. 03:07:02 REVERSE CAMERA NO SOUND. 03:08:28 WS MEETING IN WAITING AREA OF SOME SCHIZOPHRENICS. 03:08:45 CU ONE MAN SAYING WHAT HE DID LAST WEEK. 03:09:39 CU STENO PAD ON WHICH MAN IS KEEPING JOURNAL OF HIS ACTIVITIES. 03:10:37 CU MAN WRITING DOWN IN NOTEBOOK REMINDER TO HIMSELF. 03:12:22 CU COUNSELOR. 03:12:54 CU JUSTIN TALKING ABOUT WHAT HIS PLANS WERE FOR LAST WEEK. 03:15:08 COUNSELOR SPEAKS ABOUT GOALS EACH PERSON SHOULD SET FOR HIMSELF. 03:17:29 BREAK. 03:17:41 CU INTV W/ DR BREIER SAYING THAT THE MODERN ERA IN DRUG TREATMENT OF SCHIZOPHRENIA CAN REALLY BE DATED TO 1952 WHEN THORAZINE WAS STUMBLED UPON AND FOUND TO BE AN EFFECTIVE DRUG FOR CONTROLLING THE SYMPTOMS OF SCHIZOPHRENIA. AFTER THORAZINE AND ITS CLASS OF DRUGS CALLED NEUROLEPTIC DRUGS THERE WAS NO REALLY SIGNIFICANT BREAKTHROUGH FOR 40 YEARS. 03:19:39 BREIER SPEAKS ABOUT DRUG CALLED CLOZAPINE WHICH MARKED A BREAKTHROUGH EVEN THOUGH IT ACTUALLY WAS BEING DEVELOPED BACK DURING THE THORAZINE DAYS IN ATTEMPT TO IMPROVE UPON THORAZINE. 03:21:57 BREIER SAYS THE NEW CLASS OF DRUGS CAN PROVIDE PATIENTS W/ BETTER SYMPTOM CONTROL, ESSENTIALLY ELIMINATING PARKINSONIAN SIDE EFFECTS THAT ALL OF THE OLD NEUROLEPTIC DRUGS HAD WHICH INCLUDED THE ABNORMAL MOTOR MOVEMENTS, STIFFNESS, THE DROOLING THAT LED MANY PATIENTS TO STOP TAKING THE MEDICATIONS. 03:22:59 BREIER STATES THAT IT'S NOT A CURE, BECAUSE IF YOU STOP THE DRUGS, THE ILLNESS COMES BACK. 03:23:49 BREIER COMMENTS ON THE BRAIN AS THE MOST COMPLICATED ORGAN. THE MOST COMPLICATED ASPECT OF HUMAN FUNCTION IS HUMAN BEHAVIOR WHICH IS THINKING AND EMOTIONS. 03:24:08 BREIER SAYS THERE IS STILL NO ROOT CAUSE FOR SCHIZOPHRENIA. 03:24:45 BREIER EXPLAINS WHAT A TYPICAL AUDITORY HALLUCINATION IS LIKE. A LOT HAS BEEN LEARNED ABOUT THIS SYMPTOM. 03:28:47 BREIER EXPLAINS THEIR RESEARCH WHICH IS FOCUSED ON TRYING TO UNDERSTAND WHAT'S GONE WRONG IN THE BRAINS OF PEOPLE WHO HAVE SCHIZOPHRENIA. THAT'S WHERE BRAIN IMAGING TECHNOLOGY COMES INTO PLAY. 03:28:55 BREIER DESCRIBES ONE BRAIN IMAGING TECHNOLOGY CALLED PET SCANNING WHICH ALLOWS A PICTURE TO BE TAKEN OF THE FUNCTIONING HUMAN BRAIN AT THE VERY MOMENT IT IS INVOLVED IN SOME ACTIVITY. 03:31:00 BREAK.

Further excerpts from the Senate hearing on campaign finance irregularities.

COVER FTG AND INTV FOR DEBORAH AMOS CS ON BREAKTHROUGHS IN TREATING THE DISEASE OF SCHIZOPHRENIA: AUDIOTAPES OF WHAT SCHIZOPHRENICS HEAR, NEW TECHNIQUES IN BRAIN IMAGING, AND NEW MEDICATIONS. 03:00:40 MS FOUR IMAGES OF BRAIN W/ UPPER LEFT IMAGE HIGHLIGHTING REGION JUST BEHIND THE FOREHEAD KNOWN AS THE PREFRONTAL CORTEX WHERE AUDITORY HALLUCINATION IS VISIBLE ALONG W/ TWO OTHER KIND OF PSYCHOTIC SYMPTOMS, DELUSIONS OR PARANOIA AND THOUGHT DISORGANIZATION AS EXPLAINED SOT BY DR ALAN BREIER. 03:01:31 CU UPPER LEFT IMAGE. 03:02:39 SOT ON DOPAMINE WHICH IS A NEUROCHEMICAL IN HUMAN BRAIN THOUGHT TO BE INVOLVED W/ SCHIZOPHRENIA. 03:03:17 CU IMAGE OF BRAIN OF NORMAL INDIVIDUAL W/ DOCTOR'S FINGER POINTING TO HIGHLIGHTED REGION. THIS INDIVIDUAL WAS GIVEN A DRUG CALLED KETAMINE (SP?) WHICH CAN REPRODUCE SOME OF THE SYMPTOMS OF SCHIZOPHRENIA. 03:07:02 REVERSE CAMERA NO SOUND. 03:08:28 WS MEETING IN WAITING AREA OF SOME SCHIZOPHRENICS. 03:08:45 CU ONE MAN SAYING WHAT HE DID LAST WEEK. 03:09:39 CU STENO PAD ON WHICH MAN IS KEEPING JOURNAL OF HIS ACTIVITIES. 03:10:37 CU MAN WRITING DOWN IN NOTEBOOK REMINDER TO HIMSELF. 03:12:22 CU COUNSELOR. 03:12:54 CU JUSTIN TALKING ABOUT WHAT HIS PLANS WERE FOR LAST WEEK. 03:15:08 COUNSELOR SPEAKS ABOUT GOALS EACH PERSON SHOULD SET FOR HIMSELF. 03:17:29 BREAK. 03:17:41 CU INTV W/ DR BREIER SAYING THAT THE MODERN ERA IN DRUG TREATMENT OF SCHIZOPHRENIA CAN REALLY BE DATED TO 1952 WHEN THORAZINE WAS STUMBLED UPON AND FOUND TO BE AN EFFECTIVE DRUG FOR CONTROLLING THE SYMPTOMS OF SCHIZOPHRENIA. AFTER THORAZINE AND ITS CLASS OF DRUGS CALLED NEUROLEPTIC DRUGS THERE WAS NO REALLY SIGNIFICANT BREAKTHROUGH FOR 40 YEARS. 03:19:39 BREIER SPEAKS ABOUT DRUG CALLED CLOZAPINE WHICH MARKED A BREAKTHROUGH EVEN THOUGH IT ACTUALLY WAS BEING DEVELOPED BACK DURING THE THORAZINE DAYS IN ATTEMPT TO IMPROVE UPON THORAZINE. 03:21:57 BREIER SAYS THE NEW CLASS OF DRUGS CAN PROVIDE PATIENTS W/ BETTER SYMPTOM CONTROL, ESSENTIALLY ELIMINATING PARKINSONIAN SIDE EFFECTS THAT ALL OF THE OLD NEUROLEPTIC DRUGS HAD WHICH INCLUDED THE ABNORMAL MOTOR MOVEMENTS, STIFFNESS, THE DROOLING THAT LED MANY PATIENTS TO STOP TAKING THE MEDICATIONS. 03:22:59 BREIER STATES THAT IT'S NOT A CURE, BECAUSE IF YOU STOP THE DRUGS, THE ILLNESS COMES BACK. 03:23:49 BREIER COMMENTS ON THE BRAIN AS THE MOST COMPLICATED ORGAN. THE MOST COMPLICATED ASPECT OF HUMAN FUNCTION IS HUMAN BEHAVIOR WHICH IS THINKING AND EMOTIONS. 03:24:08 BREIER SAYS THERE IS STILL NO ROOT CAUSE FOR SCHIZOPHRENIA. 03:24:45 BREIER EXPLAINS WHAT A TYPICAL AUDITORY HALLUCINATION IS LIKE. A LOT HAS BEEN LEARNED ABOUT THIS SYMPTOM. 03:28:47 BREIER EXPLAINS THEIR RESEARCH WHICH IS FOCUSED ON TRYING TO UNDERSTAND WHAT'S GONE WRONG IN THE BRAINS OF PEOPLE WHO HAVE SCHIZOPHRENIA. THAT'S WHERE BRAIN IMAGING TECHNOLOGY COMES INTO PLAY. 03:28:55 BREIER DESCRIBES ONE BRAIN IMAGING TECHNOLOGY CALLED PET SCANNING WHICH ALLOWS A PICTURE TO BE TAKEN OF THE FUNCTIONING HUMAN BRAIN AT THE VERY MOMENT IT IS INVOLVED IN SOME ACTIVITY. 03:31:00 BREAK.

COVER FTG AND INTV FOR DEBORAH AMOS CS ON BREAKTHROUGHS IN TREATING THE DISEASE OF SCHIZOPHRENIA: AUDIOTAPES OF WHAT SCHIZOPHRENICS HEAR, NEW TECHNIQUES IN BRAIN IMAGING, AND NEW MEDICATIONS. 03:00:40 MS FOUR IMAGES OF BRAIN W/ UPPER LEFT IMAGE HIGHLIGHTING REGION JUST BEHIND THE FOREHEAD KNOWN AS THE PREFRONTAL CORTEX WHERE AUDITORY HALLUCINATION IS VISIBLE ALONG W/ TWO OTHER KIND OF PSYCHOTIC SYMPTOMS, DELUSIONS OR PARANOIA AND THOUGHT DISORGANIZATION AS EXPLAINED SOT BY DR ALAN BREIER. 03:01:31 CU UPPER LEFT IMAGE. 03:02:39 SOT ON DOPAMINE WHICH IS A NEUROCHEMICAL IN HUMAN BRAIN THOUGHT TO BE INVOLVED W/ SCHIZOPHRENIA. 03:03:17 CU IMAGE OF BRAIN OF NORMAL INDIVIDUAL W/ DOCTOR'S FINGER POINTING TO HIGHLIGHTED REGION. THIS INDIVIDUAL WAS GIVEN A DRUG CALLED KETAMINE (SP?) WHICH CAN REPRODUCE SOME OF THE SYMPTOMS OF SCHIZOPHRENIA. 03:07:02 REVERSE CAMERA NO SOUND. 03:08:28 WS MEETING IN WAITING AREA OF SOME SCHIZOPHRENICS. 03:08:45 CU ONE MAN SAYING WHAT HE DID LAST WEEK. 03:09:39 CU STENO PAD ON WHICH MAN IS KEEPING JOURNAL OF HIS ACTIVITIES. 03:10:37 CU MAN WRITING DOWN IN NOTEBOOK REMINDER TO HIMSELF. 03:12:22 CU COUNSELOR. 03:12:54 CU JUSTIN TALKING ABOUT WHAT HIS PLANS WERE FOR LAST WEEK. 03:15:08 COUNSELOR SPEAKS ABOUT GOALS EACH PERSON SHOULD SET FOR HIMSELF. 03:17:29 BREAK. 03:17:41 CU INTV W/ DR BREIER SAYING THAT THE MODERN ERA IN DRUG TREATMENT OF SCHIZOPHRENIA CAN REALLY BE DATED TO 1952 WHEN THORAZINE WAS STUMBLED UPON AND FOUND TO BE AN EFFECTIVE DRUG FOR CONTROLLING THE SYMPTOMS OF SCHIZOPHRENIA. AFTER THORAZINE AND ITS CLASS OF DRUGS CALLED NEUROLEPTIC DRUGS THERE WAS NO REALLY SIGNIFICANT BREAKTHROUGH FOR 40 YEARS. 03:19:39 BREIER SPEAKS ABOUT DRUG CALLED CLOZAPINE WHICH MARKED A BREAKTHROUGH EVEN THOUGH IT ACTUALLY WAS BEING DEVELOPED BACK DURING THE THORAZINE DAYS IN ATTEMPT TO IMPROVE UPON THORAZINE. 03:21:57 BREIER SAYS THE NEW CLASS OF DRUGS CAN PROVIDE PATIENTS W/ BETTER SYMPTOM CONTROL, ESSENTIALLY ELIMINATING PARKINSONIAN SIDE EFFECTS THAT ALL OF THE OLD NEUROLEPTIC DRUGS HAD WHICH INCLUDED THE ABNORMAL MOTOR MOVEMENTS, STIFFNESS, THE DROOLING THAT LED MANY PATIENTS TO STOP TAKING THE MEDICATIONS. 03:22:59 BREIER STATES THAT IT'S NOT A CURE, BECAUSE IF YOU STOP THE DRUGS, THE ILLNESS COMES BACK. 03:23:49 BREIER COMMENTS ON THE BRAIN AS THE MOST COMPLICATED ORGAN. THE MOST COMPLICATED ASPECT OF HUMAN FUNCTION IS HUMAN BEHAVIOR WHICH IS THINKING AND EMOTIONS. 03:24:08 BREIER SAYS THERE IS STILL NO ROOT CAUSE FOR SCHIZOPHRENIA. 03:24:45 BREIER EXPLAINS WHAT A TYPICAL AUDITORY HALLUCINATION IS LIKE. A LOT HAS BEEN LEARNED ABOUT THIS SYMPTOM. 03:28:47 BREIER EXPLAINS THEIR RESEARCH WHICH IS FOCUSED ON TRYING TO UNDERSTAND WHAT'S GONE WRONG IN THE BRAINS OF PEOPLE WHO HAVE SCHIZOPHRENIA. THAT'S WHERE BRAIN IMAGING TECHNOLOGY COMES INTO PLAY. 03:28:55 BREIER DESCRIBES ONE BRAIN IMAGING TECHNOLOGY CALLED PET SCANNING WHICH ALLOWS A PICTURE TO BE TAKEN OF THE FUNCTIONING HUMAN BRAIN AT THE VERY MOMENT IT IS INVOLVED IN SOME ACTIVITY. 03:31:00 BREAK.

COVER FTG AND INTV FOR DEBORAH AMOS CS ON BREAKTHROUGHS IN TREATING THE DISEASE OF SCHIZOPHRENIA: AUDIOTAPES OF WHAT SCHIZOPHRENICS HEAR, NEW TECHNIQUES IN BRAIN IMAGING, AND NEW MEDICATIONS. 03:00:40 MS FOUR IMAGES OF BRAIN W/ UPPER LEFT IMAGE HIGHLIGHTING REGION JUST BEHIND THE FOREHEAD KNOWN AS THE PREFRONTAL CORTEX WHERE AUDITORY HALLUCINATION IS VISIBLE ALONG W/ TWO OTHER KIND OF PSYCHOTIC SYMPTOMS, DELUSIONS OR PARANOIA AND THOUGHT DISORGANIZATION AS EXPLAINED SOT BY DR ALAN BREIER. 03:01:31 CU UPPER LEFT IMAGE. 03:02:39 SOT ON DOPAMINE WHICH IS A NEUROCHEMICAL IN HUMAN BRAIN THOUGHT TO BE INVOLVED W/ SCHIZOPHRENIA. 03:03:17 CU IMAGE OF BRAIN OF NORMAL INDIVIDUAL W/ DOCTOR'S FINGER POINTING TO HIGHLIGHTED REGION. THIS INDIVIDUAL WAS GIVEN A DRUG CALLED KETAMINE (SP?) WHICH CAN REPRODUCE SOME OF THE SYMPTOMS OF SCHIZOPHRENIA. 03:07:02 REVERSE CAMERA NO SOUND. 03:08:28 WS MEETING IN WAITING AREA OF SOME SCHIZOPHRENICS. 03:08:45 CU ONE MAN SAYING WHAT HE DID LAST WEEK. 03:09:39 CU STENO PAD ON WHICH MAN IS KEEPING JOURNAL OF HIS ACTIVITIES. 03:10:37 CU MAN WRITING DOWN IN NOTEBOOK REMINDER TO HIMSELF. 03:12:22 CU COUNSELOR. 03:12:54 CU JUSTIN TALKING ABOUT WHAT HIS PLANS WERE FOR LAST WEEK. 03:15:08 COUNSELOR SPEAKS ABOUT GOALS EACH PERSON SHOULD SET FOR HIMSELF. 03:17:29 BREAK. 03:17:41 CU INTV W/ DR BREIER SAYING THAT THE MODERN ERA IN DRUG TREATMENT OF SCHIZOPHRENIA CAN REALLY BE DATED TO 1952 WHEN THORAZINE WAS STUMBLED UPON AND FOUND TO BE AN EFFECTIVE DRUG FOR CONTROLLING THE SYMPTOMS OF SCHIZOPHRENIA. AFTER THORAZINE AND ITS CLASS OF DRUGS CALLED NEUROLEPTIC DRUGS THERE WAS NO REALLY SIGNIFICANT BREAKTHROUGH FOR 40 YEARS. 03:19:39 BREIER SPEAKS ABOUT DRUG CALLED CLOZAPINE WHICH MARKED A BREAKTHROUGH EVEN THOUGH IT ACTUALLY WAS BEING DEVELOPED BACK DURING THE THORAZINE DAYS IN ATTEMPT TO IMPROVE UPON THORAZINE. 03:21:57 BREIER SAYS THE NEW CLASS OF DRUGS CAN PROVIDE PATIENTS W/ BETTER SYMPTOM CONTROL, ESSENTIALLY ELIMINATING PARKINSONIAN SIDE EFFECTS THAT ALL OF THE OLD NEUROLEPTIC DRUGS HAD WHICH INCLUDED THE ABNORMAL MOTOR MOVEMENTS, STIFFNESS, THE DROOLING THAT LED MANY PATIENTS TO STOP TAKING THE MEDICATIONS. 03:22:59 BREIER STATES THAT IT'S NOT A CURE, BECAUSE IF YOU STOP THE DRUGS, THE ILLNESS COMES BACK. 03:23:49 BREIER COMMENTS ON THE BRAIN AS THE MOST COMPLICATED ORGAN. THE MOST COMPLICATED ASPECT OF HUMAN FUNCTION IS HUMAN BEHAVIOR WHICH IS THINKING AND EMOTIONS. 03:24:08 BREIER SAYS THERE IS STILL NO ROOT CAUSE FOR SCHIZOPHRENIA. 03:24:45 BREIER EXPLAINS WHAT A TYPICAL AUDITORY HALLUCINATION IS LIKE. A LOT HAS BEEN LEARNED ABOUT THIS SYMPTOM. 03:28:47 BREIER EXPLAINS THEIR RESEARCH WHICH IS FOCUSED ON TRYING TO UNDERSTAND WHAT'S GONE WRONG IN THE BRAINS OF PEOPLE WHO HAVE SCHIZOPHRENIA. THAT'S WHERE BRAIN IMAGING TECHNOLOGY COMES INTO PLAY. 03:28:55 BREIER DESCRIBES ONE BRAIN IMAGING TECHNOLOGY CALLED PET SCANNING WHICH ALLOWS A PICTURE TO BE TAKEN OF THE FUNCTIONING HUMAN BRAIN AT THE VERY MOMENT IT IS INVOLVED IN SOME ACTIVITY. 03:31:00 BREAK.

COVER FTG AND INTV FOR DEBORAH AMOS CS ON BREAKTHROUGHS IN TREATING THE DISEASE OF SCHIZOPHRENIA: AUDIOTAPES OF WHAT SCHIZOPHRENICS HEAR, NEW TECHNIQUES IN BRAIN IMAGING, AND NEW MEDICATIONS. 03:00:40 MS FOUR IMAGES OF BRAIN W/ UPPER LEFT IMAGE HIGHLIGHTING REGION JUST BEHIND THE FOREHEAD KNOWN AS THE PREFRONTAL CORTEX WHERE AUDITORY HALLUCINATION IS VISIBLE ALONG W/ TWO OTHER KIND OF PSYCHOTIC SYMPTOMS, DELUSIONS OR PARANOIA AND THOUGHT DISORGANIZATION AS EXPLAINED SOT BY DR ALAN BREIER. 03:01:31 CU UPPER LEFT IMAGE. 03:02:39 SOT ON DOPAMINE WHICH IS A NEUROCHEMICAL IN HUMAN BRAIN THOUGHT TO BE INVOLVED W/ SCHIZOPHRENIA. 03:03:17 CU IMAGE OF BRAIN OF NORMAL INDIVIDUAL W/ DOCTOR'S FINGER POINTING TO HIGHLIGHTED REGION. THIS INDIVIDUAL WAS GIVEN A DRUG CALLED KETAMINE (SP?) WHICH CAN REPRODUCE SOME OF THE SYMPTOMS OF SCHIZOPHRENIA. 03:07:02 REVERSE CAMERA NO SOUND. 03:08:28 WS MEETING IN WAITING AREA OF SOME SCHIZOPHRENICS. 03:08:45 CU ONE MAN SAYING WHAT HE DID LAST WEEK. 03:09:39 CU STENO PAD ON WHICH MAN IS KEEPING JOURNAL OF HIS ACTIVITIES. 03:10:37 CU MAN WRITING DOWN IN NOTEBOOK REMINDER TO HIMSELF. 03:12:22 CU COUNSELOR. 03:12:54 CU JUSTIN TALKING ABOUT WHAT HIS PLANS WERE FOR LAST WEEK. 03:15:08 COUNSELOR SPEAKS ABOUT GOALS EACH PERSON SHOULD SET FOR HIMSELF. 03:17:29 BREAK. 03:17:41 CU INTV W/ DR BREIER SAYING THAT THE MODERN ERA IN DRUG TREATMENT OF SCHIZOPHRENIA CAN REALLY BE DATED TO 1952 WHEN THORAZINE WAS STUMBLED UPON AND FOUND TO BE AN EFFECTIVE DRUG FOR CONTROLLING THE SYMPTOMS OF SCHIZOPHRENIA. AFTER THORAZINE AND ITS CLASS OF DRUGS CALLED NEUROLEPTIC DRUGS THERE WAS NO REALLY SIGNIFICANT BREAKTHROUGH FOR 40 YEARS. 03:19:39 BREIER SPEAKS ABOUT DRUG CALLED CLOZAPINE WHICH MARKED A BREAKTHROUGH EVEN THOUGH IT ACTUALLY WAS BEING DEVELOPED BACK DURING THE THORAZINE DAYS IN ATTEMPT TO IMPROVE UPON THORAZINE. 03:21:57 BREIER SAYS THE NEW CLASS OF DRUGS CAN PROVIDE PATIENTS W/ BETTER SYMPTOM CONTROL, ESSENTIALLY ELIMINATING PARKINSONIAN SIDE EFFECTS THAT ALL OF THE OLD NEUROLEPTIC DRUGS HAD WHICH INCLUDED THE ABNORMAL MOTOR MOVEMENTS, STIFFNESS, THE DROOLING THAT LED MANY PATIENTS TO STOP TAKING THE MEDICATIONS. 03:22:59 BREIER STATES THAT IT'S NOT A CURE, BECAUSE IF YOU STOP THE DRUGS, THE ILLNESS COMES BACK. 03:23:49 BREIER COMMENTS ON THE BRAIN AS THE MOST COMPLICATED ORGAN. THE MOST COMPLICATED ASPECT OF HUMAN FUNCTION IS HUMAN BEHAVIOR WHICH IS THINKING AND EMOTIONS. 03:24:08 BREIER SAYS THERE IS STILL NO ROOT CAUSE FOR SCHIZOPHRENIA. 03:24:45 BREIER EXPLAINS WHAT A TYPICAL AUDITORY HALLUCINATION IS LIKE. A LOT HAS BEEN LEARNED ABOUT THIS SYMPTOM. 03:28:47 BREIER EXPLAINS THEIR RESEARCH WHICH IS FOCUSED ON TRYING TO UNDERSTAND WHAT'S GONE WRONG IN THE BRAINS OF PEOPLE WHO HAVE SCHIZOPHRENIA. THAT'S WHERE BRAIN IMAGING TECHNOLOGY COMES INTO PLAY. 03:28:55 BREIER DESCRIBES ONE BRAIN IMAGING TECHNOLOGY CALLED PET SCANNING WHICH ALLOWS A PICTURE TO BE TAKEN OF THE FUNCTIONING HUMAN BRAIN AT THE VERY MOMENT IT IS INVOLVED IN SOME ACTIVITY. 03:31:00 BREAK.

COVER FTG AND INTV FOR DEBORAH AMOS CS ON BREAKTHROUGHS IN TREATING THE DISEASE OF SCHIZOPHRENIA: AUDIOTAPES OF WHAT SCHIZOPHRENICS HEAR, NEW TECHNIQUES IN BRAIN IMAGING, AND NEW MEDICATIONS. 03:00:40 MS FOUR IMAGES OF BRAIN W/ UPPER LEFT IMAGE HIGHLIGHTING REGION JUST BEHIND THE FOREHEAD KNOWN AS THE PREFRONTAL CORTEX WHERE AUDITORY HALLUCINATION IS VISIBLE ALONG W/ TWO OTHER KIND OF PSYCHOTIC SYMPTOMS, DELUSIONS OR PARANOIA AND THOUGHT DISORGANIZATION AS EXPLAINED SOT BY DR ALAN BREIER. 03:01:31 CU UPPER LEFT IMAGE. 03:02:39 SOT ON DOPAMINE WHICH IS A NEUROCHEMICAL IN HUMAN BRAIN THOUGHT TO BE INVOLVED W/ SCHIZOPHRENIA. 03:03:17 CU IMAGE OF BRAIN OF NORMAL INDIVIDUAL W/ DOCTOR'S FINGER POINTING TO HIGHLIGHTED REGION. THIS INDIVIDUAL WAS GIVEN A DRUG CALLED KETAMINE (SP?) WHICH CAN REPRODUCE SOME OF THE SYMPTOMS OF SCHIZOPHRENIA. 03:07:02 REVERSE CAMERA NO SOUND. 03:08:28 WS MEETING IN WAITING AREA OF SOME SCHIZOPHRENICS. 03:08:45 CU ONE MAN SAYING WHAT HE DID LAST WEEK. 03:09:39 CU STENO PAD ON WHICH MAN IS KEEPING JOURNAL OF HIS ACTIVITIES. 03:10:37 CU MAN WRITING DOWN IN NOTEBOOK REMINDER TO HIMSELF. 03:12:22 CU COUNSELOR. 03:12:54 CU JUSTIN TALKING ABOUT WHAT HIS PLANS WERE FOR LAST WEEK. 03:15:08 COUNSELOR SPEAKS ABOUT GOALS EACH PERSON SHOULD SET FOR HIMSELF. 03:17:29 BREAK. 03:17:41 CU INTV W/ DR BREIER SAYING THAT THE MODERN ERA IN DRUG TREATMENT OF SCHIZOPHRENIA CAN REALLY BE DATED TO 1952 WHEN THORAZINE WAS STUMBLED UPON AND FOUND TO BE AN EFFECTIVE DRUG FOR CONTROLLING THE SYMPTOMS OF SCHIZOPHRENIA. AFTER THORAZINE AND ITS CLASS OF DRUGS CALLED NEUROLEPTIC DRUGS THERE WAS NO REALLY SIGNIFICANT BREAKTHROUGH FOR 40 YEARS. 03:19:39 BREIER SPEAKS ABOUT DRUG CALLED CLOZAPINE WHICH MARKED A BREAKTHROUGH EVEN THOUGH IT ACTUALLY WAS BEING DEVELOPED BACK DURING THE THORAZINE DAYS IN ATTEMPT TO IMPROVE UPON THORAZINE. 03:21:57 BREIER SAYS THE NEW CLASS OF DRUGS CAN PROVIDE PATIENTS W/ BETTER SYMPTOM CONTROL, ESSENTIALLY ELIMINATING PARKINSONIAN SIDE EFFECTS THAT ALL OF THE OLD NEUROLEPTIC DRUGS HAD WHICH INCLUDED THE ABNORMAL MOTOR MOVEMENTS, STIFFNESS, THE DROOLING THAT LED MANY PATIENTS TO STOP TAKING THE MEDICATIONS. 03:22:59 BREIER STATES THAT IT'S NOT A CURE, BECAUSE IF YOU STOP THE DRUGS, THE ILLNESS COMES BACK. 03:23:49 BREIER COMMENTS ON THE BRAIN AS THE MOST COMPLICATED ORGAN. THE MOST COMPLICATED ASPECT OF HUMAN FUNCTION IS HUMAN BEHAVIOR WHICH IS THINKING AND EMOTIONS. 03:24:08 BREIER SAYS THERE IS STILL NO ROOT CAUSE FOR SCHIZOPHRENIA. 03:24:45 BREIER EXPLAINS WHAT A TYPICAL AUDITORY HALLUCINATION IS LIKE. A LOT HAS BEEN LEARNED ABOUT THIS SYMPTOM. 03:28:47 BREIER EXPLAINS THEIR RESEARCH WHICH IS FOCUSED ON TRYING TO UNDERSTAND WHAT'S GONE WRONG IN THE BRAINS OF PEOPLE WHO HAVE SCHIZOPHRENIA. THAT'S WHERE BRAIN IMAGING TECHNOLOGY COMES INTO PLAY. 03:28:55 BREIER DESCRIBES ONE BRAIN IMAGING TECHNOLOGY CALLED PET SCANNING WHICH ALLOWS A PICTURE TO BE TAKEN OF THE FUNCTIONING HUMAN BRAIN AT THE VERY MOMENT IT IS INVOLVED IN SOME ACTIVITY. 03:31:00 BREAK.