Animated molecular model of the drug Semaglutide (red) activating the GLP-1 receptor (blue). This activates G-protein complex inside the cell. Glucagon-like peptide-1 receptor (GLP1R) is a transmembrane protein found on the surface of cells in the pancreas and brain. It is a G protein–coupled receptor (GPCR) that mediates the action of GLP-1, a peptide hormone released by the body after food. Once activated, the GLP1R changes shape and activates the G-protein complex inside the cell, which signal the body to release insulin and control the appetite. Semgalutide is an artifical analogue of GLP-1 used to control type 2 diabetes and obesity.
Couples sit and lie in the grass at Imperial Palace grounds in Tokyo, Japan.
Japanese couples dating at Imperial Palace grounds in Tokyo, Japan. Pathway at Imperial Palace Park. Young Japanese couple seated on grass. Another young couple walks down a path hand in hand and sit on the grass. The young couple talking while seating on the grass. Japanese woman smiling. The man smiles back. Other couples in the background. Young couple talks. Another couple lying on the grass. A couple on grass. Another boy and girl lying on the grass with a picnic basket. Another couple walks hand in hand in the background. Location: Tokyo Japan. Date: May 1949.