World Nobel 3 - German, French share Nobel medicine prize, reax
NAME: WORLD NOBEL3 20081006I
TAPE: EF08/1014
IN_TIME: 11:01:45:23
DURATION: 00:02:21:17
SOURCES: AP TELEVISION/RTL/AP Photos
DATELINE: Various - 6 Oct 2008 / File
RESTRICTIONS: See Script
SHOTLIST:
RTL - No Access Germany, Austria (except: Infoscreen, ATV+), German-speaking Switzerland (except: Telezueri), Luxemburg and Alto Adige
Heidelberg, Germany - 6 October 2008
1. Harald zur Hausen, joint 2008 Nobel Prize winner, receiving applause from his colleagues, outside building
2. Cutaway of Zur Hausen holding his glasses
3. Zur Hausen walking to microphones, being applauded
4. SOUNDBITE (German) Harald zur Hausen, joint winner of 2008 Nobel Prize for Medicine:
"I did not expect a Nobel Prize. How can you expect a Nobel Prize? It's always like a little lottery. I only knew that I had been nominated on occasion, and I knew that I was nominated this year."
++NIGHT SHOTS++
AP TELEVISION
Phnom Penh, Cambodia - 6 October 2008
5. Francoise Barre-Sinoussi, joint 2008 Nobel Prize winner, talking on mobile
6. SOUNDBITE (English) Francoise Barre-Sinoussi, joint winner of 2008 Nobel Prize for Medicine:
"I don't know what to say, it is a big surprise for me, I am very moved, and I think it's a very important recognition of the science in Europe, in France in particular. For me, I am very glad that he did this announcement when I am in Cambodia because for me there is a cooperation between France, the national agency for AIDS research, and the developing countries, in particular Cambodia, it is very important."
7. Francoise Barre-Sinoussi, joint 2008 Nobel Prize winner, talking on mobile
AP Television
Abidjan, Ivory Coast - 6 October 2008
8. Back shot of President of Ivory Coast, Laurent Gbagbo, shaking hands with Leading AIDS researcher Luc Montagnier of France
9. SOUNDBITE: (French) Luc Montagnier, joint winner of 2008 Nobel Prize for Medicine:
"I am honoured to share this award with my collaborator and I think there are others who also deserve it as well as the two of us. With this, the Stockholm committee sends a strong message that shows that AIDS is a health problem for the entire world and we need to support research because AIDS is an epidemic that is ever present."
10. Montagnier seated in audience in presidency room
11. Close-up of man listening
12. Various of audience at international AIDS meeting in Abidjan
13. Leaflet on AIDS
14. Montagnier talking
AP Photos - No Access Canada/For Broadcast use only - Strictly No Access Online or Mobile
FILE: Paris, France - 14 July 2003
15. STILL of Leading AIDS researcher Luc Montagnier of France addressing the 2nd International AIDS Society Conference on HIV pathogenesis and treatment
AP Television
FILE: Paris, France - 5 June 2006
16. Mid of Montagnier speaking during interview
17. Photos on wall of Montagnier with celebrities
18. Montagnier speaking
19. Shelf with books on AIDS
20. Side shot of Montagnier
STORYLINE:
Three European scientists shared the 2008 Nobel Prize in medicine on Monday for separate discoveries of viruses that cause AIDS and cervical cancer, breakthroughs that helped doctors fight the deadly diseases.
French researchers Francoise Barre-Sinoussi and Luc Montagnier were cited for their discovery of human immunodeficiency virus, or HIV, in 1983.
They shared the award with Germany's Harald zur Hausen, who was honoured for finding human papilloma viruses that cause cervical cancer, the second most common cancer among women.
Zur Hausen, a German medical doctor and scientist, received half of the 1.4 (m) million dollar prize, while the two French researchers shared the other half.
Zur Hausen discovered two high-risk types of the HPV virus and made them available to the scientific community, ultimately leading to the development of vaccines protecting against infection.
The U.S. Food and Drug Administration approved the vaccine Gardasil in 2006 for the prevention of cervical cancer in girls and women ages 9 to 26.
The vaccine works by protecting against strains of the human papillomavirus, or HPV - including the two that zur Hausen discovered - that cause most cases of cervical cancers.
The HPV virus, transmitted by sexual contact, causes genital warts that sometimes develop into cancer.
In its citation, the Nobel Assembly said Barre-Sinoussi and Montagnier's discovery was one prerequisite for understanding the biology of AIDS and its treatment with antiviral drugs.
The pair's work in the early 1980s made it possible to study the virus closely.
That in turn let scientists identify important details in how HIV replicates and how it interacts with the cells it infects, the citation said.
It also led to ways to diagnose infected people and to screen blood for HIV, which has limited spread of the epidemic, and helped scientists develop anti-HIV drugs, the citation said.
"The combination of prevention and treatment has substantially decreased spread of the disease and dramatically increased life expectancy among treated patients," the citation said.
Barre-Sinoussi said that when she and Montagnier isolated the virus 25 years ago they naively hoped that they would be able to prevent the global AIDS epidemic that followed.
The Nobel Assembly said zur Hausen "went against current dogma" when he found that some kinds of human papilloma virus, or HPV, caused cervical cancer.
He realised that DNA of HPV could be detected in tumours, and uncovered a family of HPV types, only some
of which cause cancer.
The discovery led to an understanding of how HPV causes cancer and the development of vaccines against HPV infection, the citation said.