Doctor talks to couple for prenatal genetic consultation, amniocentesis procedure, karyotype analysis at John Hopkins Hospital
View of the John Hopkins Hospital in Baltimore, Maryland (The Johns Hopkins Hospital, N Broadway, Baltimore, MD 21205, United States). Doctor Michael Kaback, developer of the screening test for Tay-Sachs disease, talks to a couple during a prenatal chromosome consultation. The woman states, "we would like to terminate the fetus if it is a Tay-Sachs fetus." Doctor Kaback notes, "there would be no point in putting you or the fetus through whatever risk there may be associated with this procedure if in fact no action would be taken based upon the results of the test." Doctor uses ultrasound probe before treating the abdomen with antiseptic. Doctor treats abdomen with antiseptic to prepare for amniocentesis. Doctor inserts needle through patient's abdomen during amniocentesis. Illustration of a needle inserted into a pregnant uterus. Doctor extracts amniotic fluid from the abdomen. Doctor adds extracted amniotic fluid into vial. Medical technician employs various machines on extracted amniotic fluid sample from amniocentesis, including a Sonifier cell disruptor. Medical technician places sample into a Turner Fluorometer. Dr. Michael Kaback on telephone call with couple, saying, "things look great...." Two sisters consult with Dr. Richard H. Heller regarding obtaining amniocentesis tests for Down Syndrome at the John Hopkins Medical Institution Pre-Natal Diagnostic Clinic. Dr. Heller notes to them that although they are healthy themselves, they can "transmit the illness of Mongolism to your children." View of cells under microscope. Scientist looks under microscope. Scientist adds a drop of red fluid on microscope slide. Scientist photographs chromosomes under microscope. POV view of chromosomes through microscope. Scientist arranges a karyotype by cutting out images from paper and arranging them. View of a normal karyotype. View of a karyotype with extra chromosome indicating Down Syndrome. A couple listens to doctor Heller giving good news of normal test result during consultation. Woman smiles after receiving news that her baby boy shows normal chromosomes. Location: Baltimore Maryland USA. Date: December 23, 1970.